发明名称 |
COMPOSITIONS AND METHODS FOR DIAGNOSING/TREATING DISEASE BASED ON BETA-CATENIN/TRANSCRIPTION FACTOR INTERACTIONS |
摘要 |
Methods and compositions are described that are useful for diagnosing and/or treating disease arising from unwanted cell growth, preferably cancer, involving diagnosing cells for stabilized beta-catenin, or treating cells with compounds that disrupt or alter the formation of a complex consisting of beta-catenin/transcription factor, where the transcription factor is a member of the Lef/Tcf family.
|
申请公布号 |
WO9842296(A9) |
申请公布日期 |
1999.04.29 |
申请号 |
WO1998US05416 |
申请日期 |
1998.03.18 |
申请人 |
ONYX PHARMACEUTICALS, INC. |
发明人 |
POLAKIS, PAUL;RUBINFELD, BONNEE |
分类号 |
C12N15/09;A61K38/00;A61K45/00;A61P35/00;A61P43/00;C07K14/47;(IPC1-7):C12N15/12;G01N33/50;G01N33/574 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|