发明名称 CATALYTIC MONOCLONAL ANTIBODIES WITH PROTEASE ACTIVITY FOR THE SELECTIVE LYSIS OF THE PROTEIN COMPONENT OF PLAQUES AND AGGREGATES RELATED TO PATHOLOGICAL CONDITIONS
摘要 Catalytic monoclonal antibodies (abzymes) with selective protease activity in the pathologies characterized by the presence of plaques and fibrillar aggregates with protein component; methods for the preparation thereof and the use thereof as medicaments in the treatment of pathologies such as Alzheimer's disease, amyloidosis, atherosclerosis, prions diseases.
申请公布号 WO9906066(A3) 申请公布日期 1999.04.29
申请号 WO1998EP04706 申请日期 1998.07.28
申请人 ABIOGEN PHARMA S.R.L.;TRASCIATTI, SILVIA;ROSINI, SERGIO 发明人 TRASCIATTI, SILVIA;ROSINI, SERGIO
分类号 C12N15/09;A61K38/00;A61K39/395;A61P9/10;A61P25/28;A61P43/00;C07K14/47;C07K16/18;C12N5/10;C12N9/00;C12P21/08 主分类号 C12N15/09
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