发明名称 NOVEL METHOD FOR OBTAINING MICROSPHERES AND RESULTING PRODUCTS
摘要 The invention concerns the field of therapeutic or food chemistry, and more particularly the production of novel galenic forms. It concerns a novel method for obtaining microspheres with predetermined particle size distribution, containing an active principle using a matrix-forming agent made of a hydroalkane solution in the presence of a surfactant, to form an O/W emulsion of said matrix-forming agent, which consists in allowing the alkanol from the emulsion droplets to be diffused towards the continuous phase, so as to form in the droplet a coprecipitate of matrix-forming agent and active principle, in separating the microspheres, in washing and drying them to collect solid or hollow microspheres. The invention is useful in therapy, for dyes, in the food industry and as flavouring agents.
申请公布号 WO9920254(A1) 申请公布日期 1999.04.29
申请号 WO1998FR02251 申请日期 1998.10.21
申请人 PROGRAPHARM LABORATOIRES;DI COSTANZO, FRANCOIS;COUSIN, GERARD;BRUNA, ETIENNE;RAGOT, FRANCOISE;AURIAT, JEAN-PHILIPPE;MEISSONNIER, JULIEN 发明人 DI COSTANZO, FRANCOIS;COUSIN, GERARD;BRUNA, ETIENNE;RAGOT, FRANCOISE;AURIAT, JEAN-PHILIPPE;MEISSONNIER, JULIEN
分类号 A61K9/16;A61K9/50;A61K9/52;A61K47/32;A61K47/34;A61K47/38;(IPC1-7):A61K9/16 主分类号 A61K9/16
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