| 发明名称 |
An efficient method for the conversion of nitriles to amidines |
| 摘要 |
The present invention relates to processes for the conversion of nitriles to amidines in the preparation of compounds which are antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex. The compounds described herein are potent thrombolytics and useful for the inhibition of platelet aggregation in the treatment of thromboembolic disorders. |
| 申请公布号 |
AU9687098(A) |
申请公布日期 |
1999.04.27 |
| 申请号 |
AU19980096870 |
申请日期 |
1998.10.06 |
| 申请人 |
DU PONT PHARMACEUTICALS COMPANY |
发明人 |
PHILIP MA;PASQUALE N. CONFALONE;HUI-YIN LI |
| 分类号 |
A61K31/42;A61K31/4245;A61P7/02;C07D261/04;C07D413/10;C07F9/653 |
主分类号 |
A61K31/42 |
| 代理机构 |
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代理人 |
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| 主权项 |
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