发明名称 New nitric acid ester derivatives of pentaerythritol
摘要 Nitric acid ester derivatives of pentaerythritol of formula (R<1>)(R<2>)C(R<3>)-ONO2 (I) are new: R<1>-R<3> = CH2-ONO2, CH2-OR<4> or CH2-R<5>; and at least 1 of R<1>-R<3> = CH2-R<5>; R<4> = H or 1-3C alkanoyl; R<5> = glycoside radical having the alpha - or beta -configuration on C-1 of a monosaccharide optionally with 1-3C alkanoic or mineral acid fully or partly O-acylated; a uronic acid optionally with 1 3C alkanoic or mineral acid fully or partly O-acylated; a 1-3C alkyluronic acid ester optionally with 1-3C alkanoic or mineral acid fully or partly O-acylated. Use of (I) and compositions containing (I) are also claimed.
申请公布号 DE19745622(A1) 申请公布日期 1999.04.22
申请号 DE19971045622 申请日期 1997.10.16
申请人 ISIS PHARMA GMBH, 08056 ZWICKAU, DE;SCHWARZ PHARMA AG, 40789 MONHEIM, DE 发明人 MEESE, CLAUS O., DR.RER.NAT., 40789 MONHEIM, DE;DREWS, ROLAND, 40789 MONHEIM, DE;CAWELLO, ANETTE, 40789 MONHEIM, DE;PAAR, FRITZ, CHEM.-ING. (FH), 41466 NEUSS, DE
分类号 C07C203/04;C07H15/04;(IPC1-7):C07H15/04;A61K49/00;A61K31/21;A61K31/70;G01N31/00;G01N33/15;G01N33/50 主分类号 C07C203/04
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