发明名称 FORMATION OF COLLOIDAL METAL DISPERSIONS USING AMINODEXTRANS AS REDUCTANTS AND PROTECTIVE AGENTS
摘要 The invention related generally to the preparation of colloidal metal(O) particles having a crosslinked aminodextran coating with pendent amine groups attached thereto. The aminodextran acts as both a reductant for reducing metal ions to metal(O) particles and as the protective agent which coats the metal(O) particles thus formed. After stabilizing the aminodextran coating by use of a crosslinking agent, the coated particles can be used to covalently bind proteins. The resulting protein containing colloidal particles can be used as markers in optical and electron microscopy, in immunological and biological assays, and possibly as therapeutic agents.
申请公布号 CA2128230(C) 申请公布日期 1999.04.20
申请号 CA19932128230 申请日期 1993.01.28
申请人 COULTER CORPORATION 发明人 SIIMAN, OLAVI;BURSHTEYN, ALEXANDER
分类号 G01N33/532;A01N59/16;A61K9/50;A61K9/62;A61K9/64;A61K33/24;A61K39/395;A61K47/48;B01J13/00;B01J13/04;C07K1/113;C07K14/00;C07K14/42;C07K16/00;C08B35/04;C08B37/02;G01N33/548;G01N33/553;(IPC1-7):C07K17/14;C12N11/14;B22F9/24;G01N33/531 主分类号 G01N33/532
代理机构 代理人
主权项
地址