发明名称 |
FORMATION OF COLLOIDAL METAL DISPERSIONS USING AMINODEXTRANS AS REDUCTANTS AND PROTECTIVE AGENTS |
摘要 |
The invention related generally to the preparation of colloidal metal(O) particles having a crosslinked aminodextran coating with pendent amine groups attached thereto. The aminodextran acts as both a reductant for reducing metal ions to metal(O) particles and as the protective agent which coats the metal(O) particles thus formed. After stabilizing the aminodextran coating by use of a crosslinking agent, the coated particles can be used to covalently bind proteins. The resulting protein containing colloidal particles can be used as markers in optical and electron microscopy, in immunological and biological assays, and possibly as therapeutic agents. |
申请公布号 |
CA2128230(C) |
申请公布日期 |
1999.04.20 |
申请号 |
CA19932128230 |
申请日期 |
1993.01.28 |
申请人 |
COULTER CORPORATION |
发明人 |
SIIMAN, OLAVI;BURSHTEYN, ALEXANDER |
分类号 |
G01N33/532;A01N59/16;A61K9/50;A61K9/62;A61K9/64;A61K33/24;A61K39/395;A61K47/48;B01J13/00;B01J13/04;C07K1/113;C07K14/00;C07K14/42;C07K16/00;C08B35/04;C08B37/02;G01N33/548;G01N33/553;(IPC1-7):C07K17/14;C12N11/14;B22F9/24;G01N33/531 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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