New indenyl propyl azabicyclo octane methanamine derivatives with dopaminergic and serotoninergic receptor activity

摘要

Indenyl propyl azabicyclo(3.2.1)octane methanamine derivatives (I) and intermediates are new. Indenyl propyl azabicyclo(3.2.1)octane methanamine derivatives of formula (I), their pure geometric isomers or their mixtures are new. X = H or 1 or 2 MeO; Y = 1 or more H, Cl, MeO and EtO; Z' = 2 H atoms or O. Independent claims are also included for the preparation of (I) from ethyl 8-(phenylmethyl)-8-azabicyclo(3.2.1)octane-3-carboxylate and the intermediates of formula (IX). R = H or propanoyl.