EXTRACELLULAR MATRIX PRODUCTION PROMOTER

摘要

An agent which promotes the production of extracellular matrices, more particularly, acidic mucopolysaccharides such as hyaluronic acid and fibrous proteins such as collagen and thus exhibits the effects of activating the extracellular matrices, normalizing skin tissues and efficaciously preventing skin aging by reinforcing the binding between the epidermis and the dermis. This agent contains as the active ingredients the extracts of plants belonging to the genus Bupleurum such as B. scorzoneraefolium and saikosaponin and saikogenin contained in these extracts. Use of this agent as a skin preperation for external use, etc. makes it possible to promote the production of the above acidic mucopolysaccharides, fibrous proteins, etc. in fibroblasts, etc.