Combinatorial libraries comprise first oligonucleotide analogs and second oligonucleotide analogs which are coupled together to form antisense molecules capable of binding target polynucleotides and activating an RNase, and ribozymes capable of cleaving polynucleotides.
申请公布号
WO9918238(A1)
申请公布日期
1999.04.15
申请号
WO1998US20361
申请日期
1998.09.28
申请人
OASIS BIOSCIENCES, INC.;RILEY, TIMOTHY, A.;BROWN, BOB, D.;ARNOLD, LYLE, J.
发明人
RILEY, TIMOTHY, A.;BROWN, BOB, D.;ARNOLD, LYLE, J.
