| 摘要 |
<p>Heterocyclic compounds of the following formula:whereinB is [wherein R1 is hydrogen or lower alkyl;R2 is hydrogen or lower alkyl; andX is hydrogen or hydroxy protective group], lower alkanoyl or hydroxyimino(lower)alkylA is lower alkylene;W is heterocyclic or carbocyclic group, each of which may have one or more substituent(s);Z is heterocyclic group selected from the group consisting of imidazolyl, triazolyl,imidazopyridyl and adenyl, each of which may have one or more substituent(s);or a salt thereof,provided that when W is aryl which may have one or more substituent(s), then (i) Z is triazolyl, imidazopyridyl or adenyl, each of which may have one or more substituent(s); (ii) Z is imidazolyl which may have one or more substituent(s) and B is lower alkanoyl or hydroxyimino(lower)alkyl; or (iii) Z is imidazolyl which may have one or more substituent(s) and R1 and R2 are both lower alkyl.or pharmaceutically acceptable salts thereof, which are useful as a medicament.</p> |
