HYDRAULIC SURGICAL CEMENT

摘要

The cement for surgical purposes comprises three components. The first component comprises beta tertiary calciumphosphate beta -Ca3(PO4)2 ( beta -TCP) particles; and monocalcium phosphate Ca(H2PO4)2 (MCPA) or monocalcium phosphate monohydrate Ca(H2PO4).H2O (MCPM) particles or phosphoric acid. The second component comprises water. The third component comprises particles having an average diameter which is larger than the average diameter of said beta tertiary calciumphosphate beta -Ca3(PO4)2 ( beta -TCP) particles of said first component. Upon mixing of said three components a hardened mass comprising brushite CaHPO4. 2H2O (DCPD) is formed. The beta -TCP particles have a specific surface area of less than 10,000 m<2>/g and a Ca/P atomic ratio different from 1,50. The component constitutes 1 to 99 volume-percent of said hardened mass. The cements according to the invention may be used in dental and maxillofacial surgery (alveolar ridge reconstruction, dental socket filling), for orthopaedic applications (bone fracture repair, bone augmentation) and for local drug delivery (antibiotics, anti-inflammatory and anti-cancer drugs).