发明名称 METHOD FOR PREPARING LIPOSOMES WITHOUT USING AN ORGANIC SOLVENT
摘要 <p>PCT No. PCT/FR95/00012 Sec. 371 Date Jul. 31, 1996 Sec. 102(e) Date Jul. 31, 1996 PCT Filed Jan. 5, 1995Multilamellar lipid vesicles are prepared by a two-step method. In the first step, a sterol is completely dissolved in a mixture comprising an aqueous solvent and a surfactant. In the second step, a lipid surfactant is added to a solution resulting from the first step, to prepare a homogeneous lamellar liquid crystal phase or a liquid crystal phase suspension in water. The liquid crystal phase or liquid crystal phase suspension can then be converted into multilamellar lipid vesicles.</p>
申请公布号 EP0737063(B1) 申请公布日期 1999.04.14
申请号 EP19950906369 申请日期 1995.01.05
申请人 CAPSULIS 发明人 ROUX, DIDIER;DEGERT, CORINNE;LAVERSANNE, RENE
分类号 A61K8/14;A61K9/127;A61Q17/04;A61Q19/00;B01J13/02;(IPC1-7):A61K9/127;A61K7/00 主分类号 A61K8/14
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