| 摘要 |
Cosmetic and/or dermatological composition for treating keratinic fibres comprises a carrier, at least one 2-electron oxidoreductase enzyme, at least one substrate for the enzyme, and at least one substantive polymer selected from cationic cellulose derivatives, dimethyl diallyl ammonium halide homopolymers, copolymers of dimethyl diallyl ammonium halides and (meth)acrylic acid, methacryloyloxyethyl trimethyl ammonium halide homo- and copolymers, polyquaternary ammonium polymers and cationic vinylpyrrolidone polymers. Preferably the enzyme is an animal, microbial or recombinant uricase and is present in an amount of 0.01-20 (preferably 0.1-5) wt.%. The substrate is selected from uric acid and its salts and is present in an amount of 0.01-20 (preferably 0.1-5) wt.%. The substantive polymer is selected from: quaternised cellulose ether derivatives; polyquaterniums; dimethyl diallyl ammonium chloride homopolymers; copolymers of dimethyl diallyl ammonium chloride and acrylic acid; polymers comprising repeat units of formula NMeä(CHä)àNMeä(CHä)åÂí (Clî)ä and having a molecular weight of 9500-9900; polymers comprising repeat units of formula NMeä(CHä)àNEtä(CHä)àÂí (Brî)ä and having a molecular weight of 1200; polymers comprising repeat units of formula NMeä(CHä)NHCODNH(CHä)NMeä(CHä)äO(CHä)äÂí (Clî)ä, where p = 1-6, D = a bond or (CHä)CO, r = 4-7; and vinylpyrrolidone copolymers containing dimethylaminoethyl methacrylate, methacrylamidopropyl trimethyl ammonium or methyl vinyl imidazolium units.
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