A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an amount sufficient to combat the decrease of nitric oxide level associated with the presence of the APOE4 allele. Also disclosed is a method of increasing nitric oxide levels in cells in need thereof which comprises administering APOE to the cells in an amount sufficient to increase nitric oxide levels in the cells.
申请公布号
WO9916464(A1)
申请公布日期
1999.04.08
申请号
WO1998US20412
申请日期
1998.09.30
申请人
DUKE UNIVERSITY;VITEK, MICHAEL, P.;COLTON, CAROL, A.