发明名称 |
IMMUNOGENIC CONJUGATED POLYPEPTIDE FOR TREATMENT OF HERPES SIMPLEX VIRUS |
摘要 |
Peptide constructs chemically synthesized to contain a Herpes Simplex Virus specific antigenic peptide, such as, the 322-332 peptide (H1) from the ICP27 protein of Herpes Simplex Virus (HSV-1) and a peptide from a T cell binding ligand (TCBL), such as beta -2M (aa 35-50), which elicits a TH1-like response in vitro tests in mice, were protective against challenge with HSV.
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申请公布号 |
WO9916710(A1) |
申请公布日期 |
1999.04.08 |
申请号 |
WO1998US20681 |
申请日期 |
1998.09.29 |
申请人 |
CEL-SCI CORPORATION;NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE;ZIMMERMAN, DANIEL, H.;ROSENTHAL, KENNETH, S. |
发明人 |
ZIMMERMAN, DANIEL, H.;ROSENTHAL, KENNETH, S. |
分类号 |
A61K38/00;A61K39/00;A61K39/245;A61K39/385;A61P31/22;C07K14/035;C07K14/47;C07K14/74;C07K19/00;(IPC1-7):C01D1/32;C01D3/16;C01D7/26;C22B26/10;C07K14/705;A61K39/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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