| 摘要 |
<p>A polypeptide which is a constituent of a killer T cell receptor capable of injuring specifically human immunodeficiency virus-infected cells; a DNA encoding this polypeptide; a recombinant vector consisting of this DNA and a vector; a transformant obtained by transferring this recombinant vector into a host cell; a process for producing the above polypeptide characterized by culturing the above transformant in a medium, thus forming and accumulating the polypeptide in the culture and then recovering the polypeptide from the culture; an antibody reacting specifically with the above polypeptide; human-mouse type killer T cell receptor α-chain and β-chain in each of which the variable region site of the above polypeptide is sustained while the constant region site thereof has been replaced by that of the human type; transgenic animals having the above polypeptide expressed therein; and anti-HIV agents containing the above polypeptide.</p> |
