<p>A biosensor (10) has a pH-sensitive polymeric hydrogel (30) in a rigid and preferably biocompatible enclosure (20). The hydrogel (30) includes an immobilized oxidoreductase enzyme such as glucose oxidase. The oxidoreductase enzyme catalyzes a chemical reaction consuming an organic molecule and producing a byproduct. The hydrogel (30) changes its osmotic pressure in proportion to the concentration of a byproduct. By measuring the change in osmotic pressure with a pressure transducer (40), the biosensor (10) is able to accurately measure the concentration of the organic molecule without the problem of interference encountered by prior art biosensors. A battery (64) powered telemeter (60) operably engaged to the pressure transducer (40) sends a radio data signal to a receiver (66) operably attached to a computer (62).</p>
申请公布号
WO9917095(A1)
申请公布日期
1999.04.08
申请号
WO1998US20750
申请日期
1998.09.30
申请人
M-BIOTECH, INC.;HAN, IN, SUK;MAGDA, JULES, J.;BAE, YOU, HAN;BAEK, SEONG, GI
发明人
HAN, IN, SUK;MAGDA, JULES, J.;BAE, YOU, HAN;BAEK, SEONG, GI