COMBINATORIAL DIHYDROBENZOPYRAN LIBRARY

摘要

Combinatorial libraries are disclosed which are represented by Formula I: wherein: is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of the formula which interact (i.e., as agonists or antagonists) with alpha adrenergic receptors, dopamine receptors, sigma -opiate receptors, and K+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatment of ocular diseases such as glaucoma.