Compositions for cytochrome P450 biotransformation reactions

摘要

A storable biotransformation mixture that can oxidize a drug, comprising a cytochrome P450 enzyme, an electron donor; and, a buffer solution. In a preferred embodiment the mixture also contains liposomes, cytochrome b5 and NADPH-P450 reductase as the electron donor. The mixture is storable at a temperature less than 8 DEG C. to for at least two weeks and is able to oxidize a drug after storage.