| 发明名称 |
Quinolones and their therapeutic use |
| 摘要 |
1-Alkyl-substituted-quinolone-3-carboxamides have therapeutic utility via inhibition of Phosphodiesterase IV esterase and/or Tumour Necrosis Factor activity. The compounds of the invention have the general formula (I): <IMAGE> (I) The compounds of the invention encompassed by formula (I) include enantiomers, diastereoisomers and mixtures, including racemic mixtures.
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| 申请公布号 |
US5891878(A) |
申请公布日期 |
1999.04.06 |
| 申请号 |
US19960691338 |
申请日期 |
1996.08.02 |
| 申请人 |
CHIROSCIENCE LIMITED |
发明人 |
BEASLEY, STEVEN COLIN;MONTANA, JOHN GARY;DYKE, HAZEL JOHN;HAUGHAN, ALAN FINDLAY;RUNCIE, KAREN ANN;MANALLACK, DAVID THOMAS;BUCKLEY, GEORGE MARTIN;MAXEY, ROBERT JAMES;KENDALL, HANNAH JAYNE;BAXTER, ANDREW DOUGLAS |
| 分类号 |
C07D215/54;A61K31/00;A61K31/435;A61K31/439;A61K31/444;A61K31/47;A61K31/4709;A61P1/00;A61P1/04;A61P3/00;A61P3/10;A61P7/00;A61P7/12;A61P9/00;A61P11/00;A61P11/06;A61P17/00;A61P19/00;A61P19/02;A61P19/08;A61P25/16;A61P25/28;A61P27/00;A61P27/02;A61P27/16;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07D215/56;C07D401/06;C07D401/14;C07D471/04;C07D491/048;(IPC1-7):A61K31/47;A61K31/50;A61K31/505 |
主分类号 |
C07D215/54 |
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