| 摘要 |
A device and method for mixing an aspirated fluid slug (40), such as a DNA sample and reagent, within a capillary tube (28) through the electrical deflection of a diaphragm, such as a piezo-ceramic disk (12). The device (10) includes first and second mounting plates (16, 18). The piezo-ceramic disk (12) is sandwiched between two O-rings seals (14) and the two mounting plates (16, 18) to form an air seal (21) between the disk (12) and the first mounting plate (16). A first opening (24) receives an end (26) of the capillary tube (28) and extends almost completely through the first mounting plate (16) such that the end (26) is essentially perpendicular and adjacent to the disk (12). A smaller axially-aligned second opening (30) connects the air seal (21) between the disk (12) and the first mounting plate (16) to dead air volume (42) in the capillary tube (28). A third O-ring seal (34) seals the capillary tube (28) to the first mounting plate (16) at the first opening (24). A power source (44) applies a voltage to the disk (12) to produce a deflection of the disk. The deflection acts on the sealed dead air space between the disk (12) and dead air volume (42) to rapidly move the fluid slug (40) back and forth within the capillary tube (28).
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