| 摘要 |
A pH-neutral aqueous solution of a quinolone-carboxylic acid of the formula (see fig. I) in which R1 represents halogen, C1-4-alkyl or C2-4-alkenyl, R2 and R3 represent hydrogen, C1-4-alkyl, or together with the adjacent nitrogen atom form an optionally substituted morpholine or piperazine ring, R4 represents optionally substituted C1-4-alkyl or C3-6-cycloalkyl, X represents -N= or -CR5=, and R5 represents hydrogen, halogen, OH or C1-4-alkyl, or R4 and R5, together with the C and N atoms positioned between them, form a saturated 5- or 6-membered ring which can contain other hetero atoms and which is optionally substituted, the solution containing calcium ions in at least an equimolar amount relative to the quinolonecarboxylic acid and having a pH between about 6.5 and 7.5. The solution is prepared by reacting the quinolonecarboxylic acid in water with a water-soluble calcium compound in at least an equimolar ratio and subsequently adjusting the pH of the solution to a value between about 6.5 and 7.5. The solutions are especially suited for treating eggs and drinking water.
|
