发明名称 |
Asthma associated factors as targets for treating atopic allergies including asthma and related disorders |
摘要 |
A new gene in the Ras family that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and certain lymphomas or leukemias. A method for the identification and use of small molecule inhibitors of Ras to treat these disorders. A method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders and certain lymphomas and leukemias by measuring the level of Ras in biologic samples using antibody specific for the Ras protein. |
申请公布号 |
AU9495798(A) |
申请公布日期 |
1999.04.05 |
申请号 |
AU19980094957 |
申请日期 |
1998.09.18 |
申请人 |
MAGAININ PHARMACEUTICALS, INC. |
发明人 |
JEAN-CHRISTOPHE RENAULD;JAMILA LOUAHED;LUIGI GRASSO;ROY LEVITT;NICHOLAS NICOLAIDES |
分类号 |
G01N33/53;A61K31/336;A61K31/351;A61K31/366;A61K31/575;A61K38/00;A61K45/00;A61P11/08;A61P35/00;A61P35/02;A61P37/08;A61P43/00;C07K14/47;C07K14/82;C07K16/32;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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