| 摘要 |
Nucleic acid (I) encoding a peptide (II) that interacts with presenilins (III). Independent claims are also included for the following: (1) peptide (II); (2) recombinant production of (II); (3) cells transformed with (I) that produce (II); (4) oligonucleotides antisense to (I); (5) probes that hybridize with (I) or the corresponding mRNA; (6) antibodies, or their fragments, directed against (II); (7) method for detection or isolation of compounds (A) that modulate or inhibit interaction between (II) and (III); (8) ligand for (II) identified by this method; (9) recombinant, defective virus containing (I); and (10) vector containing (I). |
