发明名称 |
HYDRAZONO-BENZAZULENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND INTERMEDIATES |
摘要 |
The invention concerns products of formula (I) in which R1 represents S(O)X-[A]-[B]-COR6, x being equal to 0, 1 or 2; [A]- representing a bivalent radical derived from an aliphatic hydrocarbon, linear or branched, saturated or unsaturated, comprising 1 to 12 carbon atoms; [B] representing a phenyl radical, a CH(Z) radical or a single bond; G represents, either a radical of formula (G1) in which (Het') is a heterocycle of general formula (a), in which (H) forms, with the structural unit N=C-NH-, the residue of an aromatic or non-aromatic heterocycle, monocyclic or bicyclic, saturated or unsaturated, comprising 1 to 9 carbon atoms and 2 to 5 heteroatoms selected among oxygen, nitrogen or sulphur atoms, or a NRaRb radical (radical G2), or a (Het) radical (radical G3), or a -NRh-C(=X)-NHRc radical (radical G4), in which X is a sulphur, oxygen or NH atom, or a -NRh-SO2Rc radical (radical G5), and their additive salts with acids, bases and esters, the method for preparing them and the intermediates of said method, their application as medicines and the pharmaceutical compositions containing them.
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申请公布号 |
WO9915507(A1) |
申请公布日期 |
1999.04.01 |
申请号 |
WO1998FR02039 |
申请日期 |
1998.09.23 |
申请人 |
HOECHST MARION ROUSSEL;GENENTECH, INC.;CARNIATO, DENIS;GADEK, THOMAS, R.;GOUBET, FRANCOIS;GOURVEST, JEAN-FRANCOIS;KNOLLE, JOCHEN;MCDOWELL, ROBERT;SCHEUNEMANN, KARL-HEINZ |
发明人 |
CARNIATO, DENIS;GADEK, THOMAS, R.;GOUBET, FRANCOIS;GOURVEST, JEAN-FRANCOIS;KNOLLE, JOCHEN;MCDOWELL, ROBERT;SCHEUNEMANN, KARL-HEINZ |
分类号 |
A61K31/4164;A61K31/4184;A61K31/496;A61K31/505;A61P19/08;A61P19/10;A61P43/00;C07C49/747;C07C323/22;C07C333/04;C07D233/52;C07D235/30;C07D239/42;(IPC1-7):C07D233/52;A61K31/415 |
主分类号 |
A61K31/4164 |
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