发明名称 |
CATALYTIC ANTIBODIES AND A METHOD OF PRODUCING SAME |
摘要 |
The present invention relates generally to a growth factor precursor and its use to select production of antigen specific catalytic antibodies. Such catalytic antibodies are produced following B cell activation and proliferation induced by catalytic cleavage products of a target antigen portion of the growth factor precursor of the present invention. A particularly useful form of the growth factor precursor is as a nucleic acid vaccine. The nucleic acid vaccine of the present invention preferably further comprises a molecular adjuvant. Another aspect of the present invention comprises a growth factor precursor in multimeric form. The growth factor precursor of the present invention is useful for generating catalytic antibodies for both therapeutic, diagnostic and industrial purposes.
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申请公布号 |
CA2304365(A1) |
申请公布日期 |
1999.04.01 |
申请号 |
CA19982304365 |
申请日期 |
1998.09.18 |
申请人 |
AMRAD OPERATIONS PTY. LTD. |
发明人 |
SUESS, GABRIELE MARIA;TREUTLEIN, HERBERT RUDOLF;TARLINTON, DAVID MATHEW;KOENTGEN, FRANK |
分类号 |
C07K16/18;C12N9/00;C12N15/19;(IPC1-7):C07K16/00 |
主分类号 |
C07K16/18 |
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