摘要 |
The invention relates to a compound of formula (I), wherein R<1> is NR<3>R<4>, OR<3> or SR<3> with R<3> and R<4> being H or CnH2n+1 independently of each other and being the same or different, n being a whole number from 1 to 12; R<2> is equal to CmH2m-C(X)-Y with X being =O, =S or =N, Y being equal to OR<3>, NR<3>R<4> or SR<3>, R<3> and R<4> having the same meaning given above, and m being a whole number from 1 to 4; or R<2> is equal to CmH2m-Z-Y' with Z being a sulfonyl, phosphonyl, ether or amine group, Y' being equal to H, CnH2n+1, OR<3>, NR<3>R<4> or SR<3> then Z is sulphonyl or phosphonyl group, n, R<3> and R<4> having the meaning given above, and Y' being equal to CnH2n+1 when Z is an ether or an amine group; A, B, and D are the same or different and mean CR<5>R<6>, O, NR<7> ou S independently of each other with R<5>, R<6> and R<7> being H or CnH2n+1, independently of each other, n having the meaning given above; and C is equal to CR<8> or N with R<8> having the meaning of R<5> independently, A-B, B-C or C-D not being two identical heteroatoms; and nucleobase means thymine, uracile, adénine, cytosine, guanine, isocytosine, isoguanine, xanthine or hypoxanthine. The invention also relates to a method for producing these derivatives and to their use in pairing and/or testing systems.
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申请人 |
HOECHST AG, 65929 FRANKFURT, DE |
发明人 |
MICULKA, CHRISTIAN, DR., 65929 FRANKFURT, DE;WINDHAB, NORBERT, DR., 65795 HATTERSHEIM, DE;ESCHENMOSER, ALBERT, PROF. DR., KUESTNACHT, CH;SCHERER, STEFAN, DR., 64572 BUETTELBORN, DE;QUINKERT, GERHARD, PROF. DR., 61479 GLASHUETTEN, DE |