Verfahren zur Diagnose von frühen Krebsvorstufen der Leber und Niere
摘要
The invention relates to a method for diagnosing preliminary stages of cancer of the liver and kidney. Detection of the presence of insulin receptor substrate (IRS-1) in glycogenolytic foci (GSF) and/or mixed cellular foci (MCF) in a tissue sample or from the extracted nucleinic acid is assisted by the bonding of a specific reagent, for example an antibody or a nucleinic acid probe, and the display of the formed complex. In addition, the invention provides a method for testing substances which are suspected to cause liver or kidney cancer.
申请公布号
DE19739360(A1)
申请公布日期
1999.04.01
申请号
DE1997139360
申请日期
1997.09.09
申请人
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS, 69120 HEIDELBERG, DE
发明人
NEHRBAS, DIRK, 69123 HEIDELBERG, DE;BANNASCH, PETER, PROF. DR., 69259 WILHELMSFELD, DE;KLIMEK, FRITZ, DIPL.-BIOCHEM. DR., 69253 HEILIGKREUZSTEINACH, DE