NOVEL SUBSTITUTED 2-HYDROXY-3-[1-(1H-IMIDAZOL-4-YL)-ALKYL] BENZENOCARBOXYIMIDOAMIDES, METHOD OF OBTAINING THEM AND OPHTALMIC THERAPEUTIC AGENT

摘要

2-Hydroxy-3-[1-(1H-imidazol-4-yl)alkyl]benzenecarboximidamides and their salts, processes for their preparation and ophthalmic compositions containing them. These new compounds correspond to the general formula: in which R1 = hydrogen or C1-4 alkyl; R2 = hydrogen, hydroxyl, amino or C1-4 alkyl; R3 = hydrogen; or R2 and R3 = -CH2-CH2-. These are new compounds which are capable of lowering intraocular pressure and which can be used in the treatment and prevention of glaucoma.