| 摘要 |
<p>PyrimidoÄ1,2-aÜindole compounds of formula (I) and their isomers and salts are claimed. A,D,E,G,L,M = H, halo, CF3, CO2H, OH, 1-6C alkoxy, 1-6C alkoxycarbonyl or 1-6C alkyl optionally substituted by OH or 1-4C alkoxy; R<1>, R<2> = H, 3-8C cycloalkyl or 1-10C alkyl (optionally substituted by 3-6C cycloalkyl) or phenyl; or R<1> + R<2> = 4-8C cycloalkyl; R<3> = phenyl (optionally substituted by 1-3 NO2, CO2H, halo, CN, 2-6C alkenyl or alkoxycarbonyl or 1-6C alkyl (itself optionally substituted by OH, CO2H or 1-6C alkoxy or alkoxycarbonyl), or by one OR<4> or NR<5>R<6>); R<4> = H or 1-6C alkyl or alkenyl; R<5>, R<6> = phenyl, H or 1-6C alkyl, or 1-8C acyl optionally substituted by NR<7>R<8>; R<7>, R<8> = H or 1-8C acyl.</p> |
