发明名称 |
Stabilization of prostaglandin drug |
摘要 |
A stable solid dispersion of prostaglandin drug, particularly Misoprostol, (+/-)methyl 7-[3( alpha )-hydroxy-2- beta -(4 (RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopent-1 alpha -yl]heptanoate, comprising ammonio methacrylate copolymers. The ammonio methacrylate copolymers comprise Eudragit RS series, Eudragit RL series, Eudragit S, Eudragit L, and the mixture thereof. The stable solid dispersion is a sustained release type.
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申请公布号 |
US5889051(A) |
申请公布日期 |
1999.03.30 |
申请号 |
US19970893265 |
申请日期 |
1997.07.15 |
申请人 |
DEVELOPMENT CENTER FOR BIOTECHNOLOGY |
发明人 |
CHEN, DAVID;TSAY, RONG-JER;LIN, HUE-IN;LU, SHU-BIN |
分类号 |
A61K9/14;(IPC1-7):A61K31/215 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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