| 摘要 |
Nano-fibrils of amorphous cellulose are used as thickening agent in toothpaste formulations. Bucco-dental (toothpaste) formulations comprising at least one thickening agent containing nano-fibrils of cellulose (NFC) which are essentially amorphous and have at least 80 % cells with primary walls. Preferably the nano-fibrils of cellulose have a degree of crystallinity of less than or equal to 50 %, preferably 15-50 % and especially less than 50 %, and the amount of cells with primary walls is at least 85 wt. %.The bucco-dental formulation preferably contains 0.1-0.4 (0.15-0.3) wt.% NFC.The nano-fibrils of cellulose may be loaded on the surface with carboxylic acids and/or acid polysaccharides.The NFC may be incorporated into the formulation in a form associated with at least one organic polyhydroxy compound (I), especially where the weight ratio (I) to(I)+(NFC) is less than or equal to 50 %, preferably less than or equal to 30 %.(I) is selected e.g. from carbohydrates and their derivatives and poly-alcohols. The carbohydrates are especially 3-6 C linear or cyclic monosaccharides, polysaccharides and their fatty derivatives such as sucro-esters of fatty acids, and carbohydrate alcohols, acids or ethers. The organic polyhydroxy compounds are e.g. carboxymethyl cellulose, xanthan gum, guars, sorbitol and mixtures of these.The NFC may also be used in association with (i) compounds of formula: (R<1>R<2>N)COA (II) R<1> and R<2> = H or 1-10 C (1-5 C) alkyl; A = H, 1-10 C (1-5 C) alkyl or a group R<1>R<2>N- ;and (ii) surfactants which are preferably nonionic, anionic or amphoteric. Independent claims are included covering (a) the use of essentially amorphous nano-fibrils of cellulose in association with organic polyhydroxy compounds as thickener in bucco-dental formulations and (b) a procedure for thickening bucco-dental formulations using essentially amorphous nano-fibrils of cellulose in association with organic polyhydroxy compounds. |
