发明名称 NOOTROPIC AGENT
摘要 A drug which improves cerebral neurotransmission based on interaction of long-term activation of a protein kinase C pathway and long-term activation of presynaptic nicotinic acetylcholine (nACh) receptors, and on an accompanying increase in the amount of released glutamate, which activates cerebral neurotransmission over a prolonged period. The substances of the present invention serve as excellent nootropic. They are particularly useful for the therapy of dementia caused by hydrocephalus, or by subdural hemorrhage.
申请公布号 CA2301782(A1) 申请公布日期 1999.03.25
申请号 CA19982301782 申请日期 1998.09.14
申请人 DAIICHI PHARMACEUTICAL CO., LTD. 发明人 WATABE, SHIGEO;YOSHII, MITSUNOBU;NISHIZAKI, TOMOYUKI
分类号 C07D401/12;A61K31/00;A61K31/40;A61K31/4015;A61K31/44;A61K31/4427;A61K31/4439;A61K45/00;A61P25/00;A61P25/28;A61P43/00;C07D207/26;C07D207/27;C07D207/273;(IPC1-7):A61K45/00 主分类号 C07D401/12
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