发明名称 |
NOOTROPIC AGENT |
摘要 |
A drug which improves cerebral neurotransmission based on interaction of long-term activation of a protein kinase C pathway and long-term activation of presynaptic nicotinic acetylcholine (nACh) receptors, and on an accompanying increase in the amount of released glutamate, which activates cerebral neurotransmission over a prolonged period. The substances of the present invention serve as excellent nootropic. They are particularly useful for the therapy of dementia caused by hydrocephalus, or by subdural hemorrhage.
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申请公布号 |
CA2301782(A1) |
申请公布日期 |
1999.03.25 |
申请号 |
CA19982301782 |
申请日期 |
1998.09.14 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
WATABE, SHIGEO;YOSHII, MITSUNOBU;NISHIZAKI, TOMOYUKI |
分类号 |
C07D401/12;A61K31/00;A61K31/40;A61K31/4015;A61K31/44;A61K31/4427;A61K31/4439;A61K45/00;A61P25/00;A61P25/28;A61P43/00;C07D207/26;C07D207/27;C07D207/273;(IPC1-7):A61K45/00 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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