摘要 |
<p>A medicinal composition containing an antibody having a reactivity with human CTGF has been found out to inhibit the proliferation and migration of vascular endothelial cells and, moreover, neovascularization. It is highly useful in treating diseases and symptoms caused by the proliferation and migration of vascular endothelial cells or neovascularization (for example, diabetic retinopathy, arteriosclerosis, arterial reconstriction, chronic articular rheumatism, psoriasis, sclerema, glaucoma, proliferation or metastasis of tumor, and inflammation in various organs).</p> |