SYDNONE IMINE DERIVATIVES

摘要

Compounds represented by the following general formula (1) or pharmaceutically acceptable salts thereof: <CHEM> Äwherein Z represents -A-X-R1, a heterocycle or cycloalkyl; A represents a methylene group; X represents a sulfur atom; R1 represents a benzoyl group; R2 represents - N(R3)R4 (wherein R3 represents a methyl group; and R4 represents an optionally substituted alkyl group, etc.); or a group represented by the following general formula (2): <CHEM> äwherein R5 and R6 represent each a hydrogen atom; and Y represents a group represented by the following general formula (3): <CHEM> (wherein R4 is as defined above)üÜ. Because of having vasodilative effect, myocardial protective effect, antiplatelet aggregation effect, etc., the compounds represented by the above general formula (1) or pharmaceutically acceptable salts thereof are useful as drugs such as therapeutic medicines for angina pectoris.