| 发明名称 |
OPTICAL RESOLUTION METHOD FOR 3S-(3-CARBOXYBENZYL)-6-(5-FLUORO-2-BENZOTHIAZOLYL)METHOXY-4S-CHROMANOL |
| 摘要 |
<p>Preparative method for 3R-(3-carboxybenzyl)-6-(5-fluoro-2-benzothiazolyl)methoxy-4R-chromanol via its salt with quinine. The chromanol has the formula: (see fig. I) and is inhibitor of 5-lipoxgenase and antagonist of leukotriene receptors and is useful in the prevention or treatment of asthma, arthritis, psoriasis, ulcers, myocardinal infarction and related diseases.</p> |
| 申请公布号 |
CA2022611(C) |
申请公布日期 |
1999.03.23 |
| 申请号 |
CA19902022611 |
申请日期 |
1990.08.02 |
| 申请人 |
PFIZER INC. |
发明人 |
FRIEDMANN, ROBERT C.;QUALLICH, GEORGE J. |
| 分类号 |
C07D407/12;A61K31/425;A61P9/08;A61P9/10;A61P11/08;A61P29/00;C07B57/00;C07D277/62;C07D311/22;C07D311/42;C07D417/12;(IPC1-7):C07D417/10;C07D453/04 |
主分类号 |
C07D407/12 |
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