Bone mass anabolic composition comprising olpadronate

摘要

PCT No. PCT/EP95/05142 Sec. 371 Date Oct. 10, 1997 Sec. 102(e) Date Oct. 10, 1997 PCT Filed Dec. 27, 1995 PCT Pub. No. WO96/19998 PCT Pub. Date Jul. 4, 1996The present invention provides methods for bone mass anabolic preservation or augmentation in human or other animal subjects affected by osteoporosis or other metabolic bone disorder characterized by systemic or regional bone loss, using bisphosphonates formulations, wherein the bone mass anabolic composition contains effective non-toxic doses of [3-(N,N-dimethylamine)-1-hydroxypropylidene]-bisphosphonic acid or olpadronate or the monosodium or other pharmaceutically acceptable salt thereof.