| 发明名称 |
Dicarbonyl-containing compounds |
| 摘要 |
This invention relates to chemical compounds that contain adjacent carbonyl groups, which effectively inhibit the biological, chemical, and/or physical properties of enzymes and other medicinally-significant proteins. In particular, the invention relates to dicarbonyl compounds that are capable of acting as enzyme inhibitors, including irreversible inhibitors of HIV-1 protease.
|
| 申请公布号 |
US5886046(A) |
申请公布日期 |
1999.03.23 |
| 申请号 |
US19960588763 |
申请日期 |
1996.01.19 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
HIRSCHMANN, RALPH F.;SMITH, III, AMOS B.;SPRENGELER, PAUL;YAO, WENQING;ANDERSON, PAUL |
| 分类号 |
C07C235/36;C07C237/20;C07C271/22;(IPC1-7):A61K31/165;C07C233/05 |
主分类号 |
C07C235/36 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
