| 摘要 |
PCT No. PCT/JP95/01249 Sec. 371 Date Dec. 19, 1996 Sec. 102(e) Date Dec. 19, 1996 PCT Filed Jun. 22, 1995 PCT Pub. No. WO96/00236 PCT Pub. Date Jan. 4, 1996The invention is composed of a hederagenin derivative of the following formula or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising of this compound as an active ingredient. <IMAGE> [1] (wherein R1 represents OR11 or NR11R12. R11 and R12 may be the same or different and each represents hydrogen, alkyl that may be substituted, cycloalkyl that may be substituted, alkenyl that may be substituted, alkinyl that may be substituted, aryl that may be substituted, or a heteroaromatic group that may be substituted, R2 and R3 may be the same or different and each represents hydrogen, alkyl that may be substituted, cycloalkyl that may be substituted, alkenyl that may be substituted, alkinyl that may be substituted, acyl that may be substituted, monoalkylcarbamoyl that may be substituted, dialkylcarbamoyl that may be substituted, or alkoxycarbonyl that may be substituted, or R2 and R3 taken together represents carbonyl.) The pharmaceutical composition of the invention is effective for the therapy of nephritis.
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