| 发明名称 |
CHIMERIC RODENT/HUMAN IMMUNOGLOBULINS SPECIFIC FOR TUMOR-ASSOCIATED ANTIGENS |
| 摘要 |
Chimeric rodent/human antibodies specific for cancer cell antigens are disclosed. The antibodies are made up of variable regions for cancer antigens derived from murine immunoglobulins and constant regions from human immunoglobulins. The murine variable regions retain antigen binding specificity when attached to human constant regions.
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| 申请公布号 |
CA1340456(C) |
申请公布日期 |
1999.03.23 |
| 申请号 |
CA19870541501 |
申请日期 |
1987.07.07 |
| 申请人 |
CENTOCOR INC. |
发明人 |
SCHOEMAKER, HUBERT J. P.;SUN, LEE K. |
| 分类号 |
C12N15/02;A61K38/00;A61K39/395;A61K51/10;A61P35/00;C07H21/04;C07K16/30;C12N5/00;C12N5/10;C12N15/09;C12N15/62;C12P21/08;C12R1/91;(IPC1-7):C12N15/13;C07K19/00;C07K16/46;A61K47/48 |
主分类号 |
C12N15/02 |
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