发明名称 Process for enhancing the optical purity of 2r-{1-hydroxy- 1-trifluoromethyl- 3-cyclopropylpropyn-2yl} -4-chloroaniline
摘要 A process for enhancing the purity of 2R-[1-hydroxy- 1-trifluoromethyl- 3-cyclopropylpropyn-2-yl] -4-chloroaniline comprising the formation of an acid addition salt which is capable of rejecting the racemate in the selected organic solvent.
申请公布号 AU9041898(A) 申请公布日期 1999.03.22
申请号 AU19980090418 申请日期 1998.09.01
申请人 MERCK & CO., INC. 发明人 CHENG YI CHEN;PAUL J. REIDER;EDWARD J.J. GRABOWSKI;LUSHI TAN;RICHARD D TILLYER
分类号 C07C215/68;C07C213/10;C07C215/70 主分类号 C07C215/68
代理机构 代理人
主权项
地址