发明名称 |
REGULATION OF OSTEOCLAST FORMATION BY INHIBITION OF OSTEOBLASTIC STEM CELL FACTOR |
摘要 |
The present invention provides an inhibitor of osteoblastic stem cell factor binding and/or activity, for example, an antibody or an antisense oligonucleotide. Also provided are pharmaceutical compositions comprising these inhibitors of osteoblastic stem cell factor binding and/or activity. Further provided is a method of regulating the activity of osteoclasts, comprising the step of: inhibiting the binding and/or activity of osteoblastic stem cell factor.
|
申请公布号 |
WO9912567(A1) |
申请公布日期 |
1999.03.18 |
申请号 |
WO1998US18812 |
申请日期 |
1998.09.10 |
申请人 |
UAB RESEARCH FOUNDATION |
发明人 |
BLAIR, HARRY, C.;DONG, SAI-SAI;JULIAN, BRUCE, A. |
分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P3/14;A61P5/18;A61P19/00;A61P19/08;A61P19/10;A61P35/04;A61P43/00;C07H21/04;C07K14/475;C07K16/00;C07K16/22;C12N15/113;(IPC1-7):A61K39/395;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|