发明名称 METHODS AND COMPOSITIONS FOR TREATING CARDIAC AND RENAL DISORDERS WITH ATRIAL NATRIURETIC PEPTIDE AND TISSUE KALLIKREIN GENE THERAPY
摘要 <p>The present invention provides a method for treating a nonhypertension-associated renal disorder in a subject having a nonhypertension associated renal disorder, comprising administering to the subject a nucleic acid encoding tissue kallikrein and/or a nucleic acid encoding atrial natriuretic peptide under conditions whereby the nucleic acid encoding tissue kallikrein and/or the nucleic acid encoding atrial natriuretic peptide is expressed in a cell in the subject, thereby treating a nonhypertension-associated renal disorder. Also provided is a method of treating a nonhypertension-associated cardiac disorder in a subject having a nonhypertension-associated cardiac disorder, comprising administering to the subject a nucleic acid encoding tissue kallikrein and/or a nucleic acid encoding atrial natriuretic peptide under conditions whereby the nucleic acid encoding tissue kallikrein and/or the nucleic acid encoding atrial natriuretic peptide is expressed in a cell in the subject, thereby treating the nonhypertension-associated cardiac disorder.</p>
申请公布号 WO1999012576(A2) 申请公布日期 1999.03.18
申请号 US1998019267 申请日期 1998.09.11
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