发明名称 N-HYDROXY UREAS AND PHARMACEUTICAL COMPOSITIONS BASED THEREON
摘要 <p>PCT No. PCT/JP95/01127 Sec. 371 Date Nov. 5, 1997 Sec. 102(e) Date Nov. 5, 1997 PCT Filed Jun. 7, 1995 PCT Pub. No. WO96/40659 PCT Pub. Date Dec. 19, 1996Described herein are N-hydroxyurea compounds having the ability to inhibit the 5-lipoxygenase enzyme and having formula (I) and the pharmaceutically acceptable salts thereof. The variables are described herein. These compounds are useful in the treatment or alleviation of inflammatory diseases, allergy and cardiovascular diseases in mammals and as the active ingredient in pharmaceutical compositions for treating such conditions. <IMAGE> (I)</p>
申请公布号 CZ9703824(A3) 申请公布日期 1999.03.17
申请号 CZ19970003824 申请日期 1995.06.07
申请人 PFIZER INC. 发明人 ANDO AKEMI;STEVENS RODNEY W.
分类号 C07D277/10;A61K31/42;A61K31/421;A61K31/425;A61K31/426;A61K31/44;A61K31/535;A61K31/54;A61P29/00;A61P37/08;A61P43/00;C07D;C07D263/10;C07D263/14;C07D263/32;C07D277/20;C07D277/30;C07D413/04;C07D417/04;(IPC1-7):C07D263/10 主分类号 C07D277/10
代理机构 代理人
主权项
地址