发明名称 FUNGICIDAL AGENT WITH INCREASED BIOLOGICAL USABILITY
摘要 <p>A pharmaceutical composition comprising: i) an antifungal agent which is (-)-(2R-cis)-4-[4-[4-[4-[[-5-(2,4-difluorophenyl)-tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-[(S)-1-ethyl-2(S)-hydroxypropyl]-3H-1,2,4-triazol-3-one; ii) at least one non-ionic surfactant; and iii) a diluent. The composition enables the antifungal compound, which has very low water solubility, to have enhanced bioavailability in mammals, such as humans.</p>
申请公布号 CZ9803790(A3) 申请公布日期 1999.03.17
申请号 CZ19980003790 申请日期 1997.05.21
申请人 SCHERING CORPORATION 发明人 SANGEKAR SURENDRA A.;VADINO WINSTON A.;LEE PING I.
分类号 A61K9/20;A61K9/48;A61K31/341;A61K31/4196;A61K31/495;A61K31/496;A61K47/10;A61K47/34;A61P31/10;(IPC1-7):A61K31/495 主分类号 A61K9/20
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