发明名称 |
Vectors for the genetic selection of ligand binding proteins in microorganisms by means of signal transduction |
摘要 |
The invention relates to a process for the genetic selection in microorganisms of proteins which are capable of ligand binding, in which process a protein which is capable of ligand binding is presented extracytoplasmically and the signal of the ligand binding is passed on by signal transduction to the biosynthetic machinery of the micoorganism for the purpose of expressing a detectable and/or selectable function. In addition to this, the patent discloses microorganisms which are suitable for use in this process, as well as replicons and processes for their preparation.
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申请公布号 |
US5882924(A) |
申请公布日期 |
1999.03.16 |
申请号 |
US19970956047 |
申请日期 |
1997.10.22 |
申请人 |
BEHRINGWERKE AKTIENGESELLSCHAFT |
发明人 |
FRITZ, HANS-JOACHIM;HENNECKE, FRANK;KOLMAR, HARALD |
分类号 |
C12N1/21;C07K14/28;C07K16/44;C12N15/09;C12N15/62;C12N15/64;C12R1/19;(IPC1-7):C12N15/11;C12N15/70;C12Q1/68 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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