| 摘要 |
Aqueous two phase systems are provided which permit the extractive separation of biological materials. In a preferred embodiment, an aqueous solution of arabinogalactan defines at least one phase, and an aqueous solution of a second solute, such as a polyether, defines at least one other phase. In one embodiment, an aqueous two phase system is provided in which one phase is defined by an aqueous solution containing predominantly ultrarefined arabinogalactan, and the other phase is defined by an aqueous solution containing predominantly a polymer such as a poly(ethylene glycol). Biological materials which can be extracted and separated from mixtures using the aqueous two phase systems include cells, organelles, macromolecules and organic molecules. The aqueous two phase systems can be used in wide range of different applications including in bioconversions for the production and separation of enzyme reaction products. The aqueous two phase systems can be used to extract a wide range of biological materials from aqueous mixtures inexpensively on a large scale, while maintaining the biological activity of the materials.
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