| 发明名称 |
Inhibitors of farnesyl-protein transferase |
| 摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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| 申请公布号 |
US5883105(A) |
申请公布日期 |
1999.03.16 |
| 申请号 |
US19970825293 |
申请日期 |
1997.03.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ANTHONY, NEVILLE J. |
| 分类号 |
C07D213/57;C07D233/54;C07D233/70;C07D401/14;C07D403/10;C07D403/14;C07D409/10;C07D409/14;C07D413/06;C07D417/06;C07D417/14;(IPC1-7):A61K31/44;C07D401/04;C07D213/53 |
主分类号 |
C07D213/57 |
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