| 发明名称 |
Process for N-desmethylating erythromycins and derivatives thereof |
| 摘要 |
Disclosed is an improved and efficient process for N-desmethylating the 3'-amino nitrogen of erythromycins and for converting the 3'-N-desmethylated erythromycins into 3'-N-substituted derivatives of 8,9-anhydro-erythromycin 6,9-hemiketals.
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| 申请公布号 |
US5883236(A) |
申请公布日期 |
1999.03.16 |
| 申请号 |
US19970974085 |
申请日期 |
1997.11.19 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
HENGEVELD, JOHN E.;DONG, XIAOXING;GUPTA, ASHOK K.;COPP, JR., RICHARD R.;PREMCHANDRAN, RAMIYA H. |
| 分类号 |
A61K31/7042;A61K31/7048;A61P31/04;C07H17/08;(IPC1-7):C07H1/00 |
主分类号 |
A61K31/7042 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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