发明名称 |
N-TERMINAL MODIFICATIONS OF RANTES AND METHODS OF USE |
摘要 |
N-terminally modified RANTES derivatives are disclosed. The derivatives effectively block the inflammatory effects of RANTES, and are useful for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, and rheumatoid arthritis. Additionally, the compounds are useful for the treatment of HIV infection.
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申请公布号 |
WO9911666(A1) |
申请公布日期 |
1999.03.11 |
申请号 |
WO1998US18204 |
申请日期 |
1998.09.02 |
申请人 |
GRYPHON SCIENCES |
发明人 |
OFFORD, ROBIN, E.;THOMPSON, DARREN;WILKEN, JILL |
分类号 |
A61K38/00;A61K38/19;A61P9/10;A61P17/00;A61P29/00;A61P31/18;A61P37/08;C07K14/52;(IPC1-7):C07K14/52 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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